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(Biochemical Pharmacology 2019) established that NNMT protein expression is elevated ~3-fold in aged skeletal muscle compared to young muscle in preclinical models, and that 5-amino-1MQ treatment was associated with altered muscle stem cell (muSC) proliferation and differentiation endpoints in C2C12 myoblast research systems

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3.8.3 Pyroptosis Pyroptosis is a novel type of PCD, distinct from apoptosis and autophagy

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Tolosa et al., 2013