Cloning the GLP-1 receptor Another important chapter was opened up for understanding the biology of GLP-1 by the cloning of the GLP-1 receptor
Healthy Fats: Sustained GLP-1 Through Bile Acid Signaling Dietary fats trigger GLP-1 release through multiple pathways direct activation of fatty acid receptors on L-cells (GPR40 and GPR120), and indirectly through bile acid signaling via the TGR5 receptor
L-cells in the distal small intestine release GLP-1 and K-cells higher up release GIP, priming the pancreas for incoming nutrients
US Food & Drug Administration
These medications work best when paired with sustainable lifestyle habits like balanced eating, regular activity, good sleep, and stress management, along with ongoing support from a healthcare provider
Long-acting injectables designed for monthly dosing (as opposed to the current standard of weekly) are also advancing