glp 1 feeling cold Do you feel on a GLP-1? Dr Weiss explains a possible reason as to why this might be happening. #joinfridays #glp1 #cold Why do GLP-1s do this?

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When peptides receive attention from highlevel policy discussions or government figures, it further legitimizes public curiosity

No side effects except fatigue for the first week or so

PERIOD2 is a circadian negative regulator of PAI-1 gene expression in mice

doi: 10.1016/j.bbi.2018.08.010 98 MoshkelgoshaSMasettiGBerchner-PfannschmidtUVerhasseltHLHorstmannMDiaz-CanoSet al

Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA 1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent