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They improve blood sugar control by lowering HbA1c levels and increasing the likelihood of reaching healthy glucose targets

Some patients may experience dramatic improvements with relatively modest weight loss, while others require more substantial weight reduction to achieve similar benefits

They may experience an enlarged spleen, gallstones or, after many years of deficiency, mental problems

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Healthcare providers note that this isn't a direct effect of the medication but rather a result of reduced protein intake and insufficient exercise during treatment

Therapeutic Strategy The im ediments to instituting a therapeutic strategy based on augmentation of a critical neurotrophic factor system for the treatment of PD are several