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Individuals with eating disorders require specialized evaluation before considering weight loss medications

Studies involving patients with severe organic diseases (e.g., cancer, chronic kidney disease) to avoid confounding effects of underlying conditions on inflammation or depression outcomes

This allows once-weekly dosing and creates sustained GH/IGF-1 elevation

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According to Cancer Research UK, hyperinsulinaemia and insulin resistance have been linked to increased breast cancer risk and potentially recurrence, suggesting that medicines improving these metabolic parameters could hypothetically offer indirect benefits