Studies in animal models focusing on diet-induced obesity provide substantiating evidence that an organisms diet profoundly affects the immune system
Multiple studies have shown that it can reduce the incidence of age-related diseases, such as cardiovascular and neurological diseases and cancer, as well as overall mortality56 in both diabetic and nondiabetic individuals.57 Animal studies have also shown an increase in lifespan.58 The ongoing Targeting Aging with Metformin (TAME) trial is a large multicenter trial evaluating the effects of metformin on human aging.59 We did not find any clinical studies analyzing its use in skin aging
Systemic exenatide treatment can reverse aging-associated transcriptomic changes in various brain cell types in mice, including glial and neurovascular cells
Early pilot studies have shown promising results related to antioxidant support, immune response, and reducing markers of oxidative stress
GHK also prevents damaging effects of lipid peroxidation, by binding its by-products such as acrolein and 4-hydroxynonenal [33,34]
This energy is essential for the maintenance of RBCs shape, membrane deformability and regulation of sodium-potassium pump [1, 2]
