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Similar to SIRT3, SIRT6 is also activated by fucoidans

There has been a large phase 3 clinical trial programme, SURMOUNT, undertaken in people who do not have diabetes

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doi: 10.1016/j.immuni.2019.03.012 17 EichhornPJRodonLGonzalez-JuncaADiracAGiliMMartinez-SaezEet al

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[1] [2] For weight management in adults with obesity or overweight with weight-related comorbidities, the same molecule is marketed as Zepbound in the UK