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The standardized mean difference (SMD) and 95% confidence interval (CI) used to compare the effect size ( 2 + SD final 2 ) (2 0.5 SD baseline SD final)] ( 2 estimation ( 2 values less than 25% as low heterogeneity, values between 25 and 50% as moderate heterogeneity, and values exceeding 50% as high heterogeneity

The targets worth the investment are those with complex bioequivalence requirements (reducing competitive density), large revenue bases (making first-filer economics compelling), and LOE timelines that align with your facility qualification and regulatory filing capacity

The most common side effects of Mounjaro are gastrointestinal, including nausea, diarrhoea, vomiting, constipation, and abdominal discomfort

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