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Klausner, M

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In the brains of Alzheimers disease (AD) patients, pathological features such as reduced mitochondrial membrane potential (m), accumulation of mitochondrial peroxides, aberrant opening of the mitochondrial permeability transition pore (mPTP), and mitochondrial iron (mFe) overload are commonly observedeach closely linked to ferroptosis induction (Chen et al., 2023

Liraglutide shows similar effects, but with shorter receptor engagement due to lower molecular stability