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In PCa, the enlarged prostate obstructs the urethra, leading to difficulties in urination

Furthermore, regardless of the treatment, the expression levels of the AR and DKK1 gene in the KO group were always significantly lower than those in the control group

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It has also been demonstrated that inhibition of S -adenosylhomocysteinase using 9-(S)-(2,3-dihydroxypropyl)-adenine (DHPA) in tobacco seeds resulted in global hypomethylation of DNA (Fulnecek et al., 2011)

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RNA interference in adult mice