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The plates were then incubated under either normoxic conditions (21% O 2 ) or hypoxic conditions (3% O 2 ) for a duration of 48 h

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Consistently, by ChIP assay, we detected significant NRF2 binding in Nqo1 and Slc7a11 loci, along with induced association of H3K4Me4 and H3K9Ac after DMF treatment (Fig