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Injectable Peptides: Deep Systemic Action for Longevity Injectable peptides are typically administered under the skin or intramuscularly, allowing them to bypass the digestive tract and reach systemic circulation directly

MOTS-c is different

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The lysate was filtered with a 0.45 m filter and loaded onto a Ni-NTA (Carl Roth, Germany) gravity column equilibrated with buffer A (20 mM sodium phosphate pH 7.5, 500 mM NaCl and 12.5 mM imidazole)

Since the peptide is stable in the gut, it can be delivered without special carriers or currently known toxicity