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There is also a reason the combination is difficult to test cleanly: because both compounds act on overlapping repair pathways (angiogenesis, cell migration), a study of the two together struggles to attribute any observed effect to either one

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The FTO gene (rs9939609) affects baseline metabolic rate and predisposition to weight gain

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doi: 10.1016/j.nicl.2018.07.011 51 CockshellSJMathiasJL

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