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This is a positive sign, not a problemit reflects improved metabolic function and requires only a simple laboratory adjustment

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Additionally, their neutral or hydrophilic surfaces may limit epithelial endocytosis

This matters practically: the compound is not simply "wearing off and restoring" each week

A synergistic effect was also observed, wherein the values of duration of the added mean durations of both monotherapies independently was substantially less than the mean duration of multiple agent therapies, all at the same dose levels for each component