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doi: 10.1210/jc.2014-3018 166

Needle Insertion: Hold the syringe like a pencil and insert the needle quickly and smoothly at a 90-degree angle into the skin

Therefore, there is a physiological basis for using the plasma BDNF as a functional surrogate for brain omega-3 FA levels, unlike the erythrocyte omega-3 FA levels, which are metabolically unrelated to the brain levels