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Poor sleep can also dull fullness cues, making it easy to eat more than you need, while making blood sugar harder to keep steady

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Salivary secretion depends on finely tuned receptor activity, and sustained activation may paradoxically reduce glandular responsiveness, contributing to the salivary hypofunction

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However, consistent benefits on hard outcomes have not been demonstrated across CKD settings, likely reflecting heterogeneity (baseline vitamin D status, stage, co-therapies, endpoints) and formulation/dosing differences (D vs