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The middle-aged man with metabolic syndrome Men in their 40s and 50s with the classic pattern of elevated blood sugar, high triglycerides, low HDL cholesterol, high blood pressure, and central obesity represent a significant portion of tirzepatide users

The second drug currently on the market, the tirzepatide found in Mounjaro and Zepbound, resembles GLP-1 in addition to another hormone called GIP, hitting receptors for both in the brain

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It is also recommended to NOT become pregnant while using either medications

GSTM2 overexpression suppresses hepatic steatosis Although GSTM2 was up-regulated in mice with hepatic steatosis, we also overexpressed this protein in mouse model fed with MCDD (Supplementary Fig

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