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Legius E, Dierick H, Wu R, Hall BK, Marynen P, Cassiman JJ, et al

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Mitochondria affect ferroptosis at the level of the cytosolic iron pool regulation by fine-tuning the iron influx from the cytosol into mitochondria, at the level of electron transport chain by adjusting mitROS generation and oxidative phosphorylation via AMPK activation in the energy-deficient state, and at the level of tricarboxylic acid (TCA) cycle affecting the content of NADPH and GSH [162, 166]

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Well monitor you closely and adjust the dosage at the first sign of side effects

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PlateletNET aggregates further amplify coagulation and inflammatory signaling, creating a feed-forward loop that compromises capillary perfusion and tissue oxygen delivery [56]

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