The amount of free radicals produced by our cells becomes consistently higher than normal and overwhelms our glutathione production capacity*.
The mice were pretreated with dopamine antagonist haloperidol (5.0 mg/kg i.p.) and subsequently treated with amphetamine (20 mg/kg i.p.1, 2, 4 and 10 days after haloperidol pre-treatment), which is usually used for the study of behavioral supersensitivity to an amphetamine stimulating effect
This is the first time scientists have shown this, and the results were published in a major scientific journal
PLoS Genet 7 , e1002424 (2011)
Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation
~ AlphaMD You check your lab results online, see the hematocrit number sitting at 54, and suddenly you're Googling "thick blood" and "stroke risk" at two in the morning