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The glucagon agonism is designed to boost hepatic energy expenditure and reduce fat storage, potentially offering a different efficacy and side effect profile compared to GIP/GLP-1 targets
Fralick, Zinman
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Rosiglitazone monotherapy in mild-to-moderate Alzheimers disease: results from a randomized, double-blind, placebo-controlled phase III study
The mechanism of action includes stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and promoting satietyall of which contribute to better blood glucose management
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