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1, 2, and 3 in the original) Preparation and storage Research-only handling information

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Neuronal cell death

Genetic Predispositions and Individual Side Effect Risk Emerging research suggests that variations in GLP-1 receptor (GLP1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) genes may influence gastrointestinal tolerability and nausea severity

Suppositories provide very similar results to IV methods of administration since the ingredients in the suppository are absorbed by the wall of the rectum and carried straight into the systemic circulation (circumventing the entero-hepatic portal system where ingredients are broken down)

S2CID 22192911