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Rethinking antiphospholipid syndrome to guide future management and research

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Also, the spinal cord of EAE mice treated with DPN display increased activation of Akt/mammalian target of rapamycin (mTOR) axis, which is not observed in a cohort of EAE mice with conditional deletion of ER (Khalaj et al., 2016)

Carbamidomethylation was set as a fixed modification, whereas methionine oxidation, asparagine and glutamine deamination, and glycosylation options were set as variable modifications, according to published data (Lebede et al., 2021)

Enzymatic combinatorial synthesis and inhibitor screening Combinatorial biocatalysis is the enzymatic version of combinatorial synthesis, involving the use of cascaded enzymatic transformations for library construction 54,55,56

In a rodent study, this increase in growth hormone production and availability caused mice to gain body weight without increasing their organ weight, which is a concern with the administration of exogenous growth hormone [26]