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A 2025 body-composition substudy added detail on fat-mass versus lean-mass changes within the T2D Phase 2 cohort fat mass accounted for the majority of total weight reduction (PMID 40609566)

TFAME derivatives of the protein hydrolysate were resuspended in dichloromethane and transferred to injection vials for SIM-GC/MS analysis

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In in vivo models (DIO mouse, ZDF rat, GLP-1R-/- transgenic mouse) its effect on glucose homeostasis, body weight, lipid profiles, -cell function and markers of neurodegeneration and cardioprotection is studied