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In most cases, adjusting your training zones is an effective strategy until your body adjusts to the medication

However, compared to small molecule inhibitors, the discovery of small molecule activators is much more challenging ( ex vivo assays

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10.1016/j.cgh.2015.01.015 117 ZhengY.YuT.TangY.XiongW.ShenX.JiangL.et al (2017)

For example, MG treatment in mouse tumor models enhances macrophage phagocytosis and increases splenic CD8 and CD4 T-cell counts, thereby elevating immune cytotoxicity (125, 126)