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The half-life of natural GLP-1 is very short
The review notes, however, that the degree to which these benefits are independent of weight loss may vary by condition, and further research is needed to elucidate these mechanisms fully
Patients often ask whether GLP1 medications might help with depression , especially when used for weight loss or diabetes management
But many patients pursuing weight loss also have orthopedic barriers that limit exercise: knee pain, hip pain, tendon problems, back pain, prior injuries, or deconditioning