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Fat loss, particularly visceral fat loss, decreases the secretion of pro-inflammatory cytokines

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Acute pancreatitis can cause severe upper abdominal pain, persistent vomiting, fever, elevated pancreatic enzymes, tissue necrosis, infection, and, in severe cases, organ failure requiring intensive medical treatment

The INS gene is located on chromosome 11p15.5 and is composed of 3 exons that generate four alternatively spliced mRNAs, all of which encode the same 110 amino acid preproprotein

Melasma is caused by UV light exposure and/or hormonal changes (most often during pregnancy)

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