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Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4

In other words: It's supposed to be more effective

One of the most famous of these enzymes is cathecol-O-methyltransferase (COMT), which is known for its role in metabolizing estrogens and catecholamines

Brain and Nerve Cell Function

Also useful as an anti-inflammatory for arthritis and athletic recovery, hormone balancing (PMS/cramps), and mood support by helping produce serotonin