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The rats in the OA-1, OA-5, OA-10, OA-20 and OA-28 groups received an intraarticular injection of MIA and were sacrificed after 1, 5, 10, 20 and 28 days, respectively after intraarticular injection of MIA

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A Lilly-funded head-to-head study published in 2025 showed Zepbound delivering stronger weight-loss outcomes than Novo's Wegovy, including greater waist reduction and a higher likelihood of patients losing at least 25% of their body weight over 72 weeks

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