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PBMs have responded to gene therapies through a combination of prior authorization requirements (which serve as the primary utilization management tool), outcomes-based payment arrangements with manufacturers, and in some cases, carve-out arrangements where gene therapy coverage is managed separately from the standard pharmacy benefit

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Hims' intake process does not require or routinely request bloodwork

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UC is characterized by frequent bloody diarrhea, pain, fatigue, and progression, and more than 1/3 of patients require hospitalization or surgery

10.1016/j.cellsig.2017.11.004 [DOI] [PMC free article] [PubMed] [Google Scholar] Laurent C, Eddarkaoui S, Derisbourg M, Leboucher A, Demeyer D, Carrier S et al (2014) Beneficial effects of caffeine in a transgenic model of Alzheimers disease-like tau pathology