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Rapid injection: Delivering the solution quickly deposits a concentrated volume of the compound into a small area of tissue all at once, giving the surrounding tissue less time to equilibrate with the pH shift
This creates an elevated TIMP:MMP ratio that correlates with collagen and elastin synthesis stimulation
Sulfapyridine increases the sensitivity of leukemia to chemotherapeutic agents by inhibiting SLC7A11 activity and cystine uptake
Kazemi A, Noorbala AA, Azam K, Eskandari MH, Djafarian K
It should be noted that these fluorescence-based biodistribution studies provide qualitative and semi-quantitative information on local retention and tissue distribution rather than quantitative pharmacokinetic data, and no conclusions regarding systemic absorption or clearance kinetics were drawn from these experiments [34]
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