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Lancet Diabetes Endocrinol 7(7):515527 Yamada Y, Katagiri H, Hamamoto Y, Deenadayalan S, Navarria A, Nishijima K, Seino Y (2020) Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes N Engl J Med

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Additionally, NAC shows protective effects in chronic conditions marked by GSH depletion, including respiratory infections, cystic fibrosis, and diabetes (Rosa et al., 2018

After significant weight loss, metabolic adaptation occursthe body's energy expenditure decreases beyond what would be predicted by the loss of body mass alone