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Metabolic studies Animals were given either 6 g/kg glucose or distilled water (2 mL/100 g body weight, n = 10 for all groups) by gavage every 6 h (at 06:20, 12:20, 18:20, and 24:20 h) for 38 days, defined as the long-term oscillating glucose (LOsG) or sham group

It closes that section by telling readers to consult a qualified provider before initiating any transition

[DOI] [PubMed] [Google Scholar] 32.Neuen B.L., Oshima M., Perkovic V., et al

If the lower doses are well-tolerated, the dose can then be increased to 0.5 mg and eventually to 1 mg or 2 mg once weekly

I think we expected to see an effect but maybe not necessarily quite such a profound effect

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