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10.1073/pnas.0813361106 34 ChenW
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Its simultaneous activation of three receptor pathways GLP-1R for appetite suppression and insulin secretion, GIPR for augmented insulin response and central appetite modulation, and GCGR for energy expenditure and hepatic fat mobilisation produces metabolic effects that exceed what single or dual agonism can achieve [4][8][9]
Drug interactions : You might experience issues when mixing peptides with medications
Biofizika 55(6):11081116 Washington TA, White JP, Davis JM, Wilson LB, Lowe LL, Sato S, Carson JA (2011) Skeletal muscle mass recovery from atrophy in IL-6 knockout mice