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10.1016/j.japh.2023.10.002 35 WeiW.JiangW.HanT.TianM.DingG.LiY.et al (2021)

By taking both, you are essentially supporting the liver from two different angles

Most patients dont bother, and they churn when friction is high and cognitive load is higher

Arch Intern Med 170(3):256261

1 When these receptors are activated by bile acids, they turn on metabolic pathways involved in reducing inflammation, metabolism, and detoxification, including the detoxification of estrogen 5 to keep estrogen balanced

The most critical factor in dosing frequency is the half-life of the medication