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Other clear candidates include patients with BMI 35+ who have tried and failed multiple structured weight loss approaches, patients with obesity plus severe sleep apnea, and patients with a metabolic syndrome phenotype where reducing insulin resistance matters

Prior subclinical marrow failure is generally assumed in these situations, however subsequent proliferative mutations inside a PNH HSPC are another possibility (133)

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They can answer your questions, monitor your progress, and adjust your plan as needed

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Your GP can review your overall treatment plan, assess whether the skin changes are related to Saxenda or other factors, and provide tailored advice