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Choosing a clinic that provides ongoing monitoring, nutritional guidance, and a clear exit strategy makes the experience significantly smoother than managing it alone

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Methods Data source and ethics This study was approved by the VUMC Institutional Review Board (IRB

Tap et al., 2020)

Collectively, the integrated therapeutic strategies targeting ferroptosis, pyroptosis, and necroptosisincluding RCD inducers combined with ICIs, nanotechnology-driven precision delivery systems, and multi-targeted approaches to overcome metabolic plasticity and off-target toxicitiesprovide a comprehensive framework to enhance melanoma immunotherapy efficacy ( Figure 4 )

Indian J Surg 85 , 14941495 (2023)