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Someone who is anorexic is much more likely to have a heart attack and far more likely to have cholesterol issues because of that condition. A few other situations dont rule you out automatically, but they do call for extra caution and a real conversation: a history of gallbladder disease, diabetic retinopathy (rapid weight loss can temporarily make it worse), and any history of an eating disorder, which warrants screening before treatment starts

Moreover, GLP-1 expressed in the liver has been reported, while no other publications showed its expression in hepatocytes (44)

472 Promoting the urinary excretion of sodium and water reduces fluid retention and hypervolaemia, thereby reducing the load on the heart

Key: - Compatible: Safe to run together