In 2003, for example, a multi-year study published in Neuroendocrinology Letters found that epithalamin could normalize the basic functions of the human organism, potentially extending lifespan by improving cardiovascular, endocrine, immune, and nervous function, as well as homeostasis and metabolism.2 Several publications including two systematic reviews in Advances in Gerontology have corroborated such findings.3 4 Researchers believe that epitalons therapeutic qualities may be due to the following mechanisms of action: Telomere elongation Telomeres are caps of DNA sequences at the ends of chromosomes
Typical doses range from 250-1000 mg daily, though clinical evidence supports only modest benefits at lower doses
Low levels are linked to chronic diseases like diabetes and heart disease
- Mood and Libido Enhancement: Some users report improved mood and libido
I do think the high folate w/ the (absent?) B12 is suspicious
The resulting acyl-phosphate intermediate undergoes nucleophilic attack by the -amino group of cysteine, which may be activated by an active site glutamate