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This sequential/parallel action provides rationale for combination use in research settings

Treatment significantly reduced levels of pro-inflammatory cytokines including interleukin-1 (IL-1) and tumor necrosis factor- (TNF-) while increasing anti-inflammatory interleukin-10 (IL-10) expression

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this is an important caveat for researchers designing receptor-binding studies, as it distinguishes this compound from peptides with a well-defined single-receptor mechanism

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