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Vitamin E acts as a regulator of cellular metabolism, and its deficiency leads to anaemia, dysregulation of energy metabolism, irregular mitochondrial function, and tissue damage resulting from increased lipid peroxidation (170)

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Understanding this is the foundation for understanding why dosing is not a one-size-fits-all figure: the molecule behaves differently from the compounds people often group it with

Supports energy and metabolism

Interestingly, human ghrelin, which has two amino acids different from mouse ghrelin, can traverse the mouse BBB bidirectionally using saturable transport mechanisms (54)