glp-1 secretion mechanism of action of [25] Recent updates on GLP-1 agonists:

Heart and blood vessel protection- Keeps blood vessels healthy, reduces bad cholesterol oxidation, and supports normal blood pressure

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In a study comprising 16 patients with T2DM and 12 non-diabetic controls, flow-mediated vasodilation was enhanced in both groups by GLP1 infusion of 0.4 pmol/kg/min, administered during a 2-hour hyperglycemic clamp [106]

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There are several explanations for the differences in the effect of the two GLP-1RAs tested in the present study