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B12 shots are usually given into a muscle, like your upper arm or thigh

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That being said, an alternative measure was used by the research team that assessed motor function by grading the toe and heel foot print characteristic on a scale from 0-4, with 0 defined as no print, non functional, and 4 defined as complete print, near normal functioning [2]

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AP-1, HIF-1 and stress pathways