De Felice FG, Vieira MN, Bomfim TR, Decker H, Velasco PT, Lambert MP, et al
In the CY 2026 OPPS/ASC proposed rule, we proposed to continue assigning CPT code 0220U to status indicator Q4 under OPPS

Abbreviations AD: Atopic dermatitis ACD: Allergic contact dermatitis AMPK: 5AMP-Activated protein kinase G6PD: Glucose-6-phosphate dehydrogenase GALT: Gut-associated lymphoid tissue GLP-1: Glucagon-like peptide-1 GPR41: G protein-coupled receptor 41 GPR43: G protein-coupled receptor 43 IFN-: Interferon- IL-2: Interleukin-2 IL-1: Interleukin-1 IL-6: Interleukin-6 IL-8: Interleukin-8 IL-10: Interleukin-10 IL-12: Interleukin-12 IL-17: Interleukin-17 IL-19: Interleukin-19 IL-23: Interleukin-23 LPS: Lipopolysaccharide MLKL: Mixed lineage kinase domain like pseudokinase mTORC1: mammalian target of rapamycin complex 1 NF-B: Nuclear factor kappa B RCT: Randomized clinical trial ROS: Reactive oxygen species SCFA: Short-chain fatty acid T2D: Type 2 diabetes TGF-: Transforming growth factor- TLR: Toll-like receptor TNF-: Tumor necrosis factor- Treg: Regulatory T cells UVB: Ultraviolet B VEGF: Vascular endothelial growth factor References Daniel CP, Sittig KM, Wagner MJ, Cade C, Chriss W

It is involved in regulating sleep, particularly in promoting rapid eye movement (REM) sleep
Induced sputum and bronchoalveolar lavage as tools for evaluating the effects of inhaled corticosteroids in patients with asthma
Pain Management and Neurological Support: IV administration of magnesium, medically supervised ketamine, and other neuroprotective agents treats migraines, chronic pain, fibromyalgia, and mood disorders