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The involvement of lysosomal iron translocating to the mitochondria through the calcium uniporter has also been suggested in APAP-induced MPTP opening [102,103] implying that reactive oxygen species formation through the iron-mediated Fenton reaction could also be an amplifying source to ultimately cause mitochondrial dysfunction

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Precise drug delivery by dendrimer nanoparticles is easily achieved by surface targeting, and folate-targeted dendrimers in particular are a relevant choice in cancer therapeutics, because cancer cells overexpress the folate receptor

2021 Aug 2;12(8):1201

Oberley, L.W