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Impaired healing: senescent cells help wound repair, so clearing them at the wrong time may not be wanted

In clinical trials of oral semaglutide for T2DM, cholelithiasis was reported in 1% of patients-treated with semaglutide 7 mg PO

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While most are approved for the management of type 2 diabetes, some formulations, such as semaglutide (Wegovy) and tirzepatide (Zepbound), have also been approved for chronic weight management in adults with obesity or overweight