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It is contraindicated for use in neonates and premature infants due to the risk of serious adverse reactions, including gasping syndrome

J Biol Chem 2005;280:3961639626

Other potential long-term complications include: Decreased lung function Depression due to slower mental functioning An abnormal enlargement of the thyroid gland (goiter) Heart issues, including high cholesterol and heart disease Infertility in women, due to the inability to ovulate from lack of thyroid hormones Inability to lose weight Nerve damage in the arms, legs, and feet (peripheral neuropathy) Delayed physical and intellectual development in babies born to mothers who are hypothyroid Delayed development in children with untreated hypothyroidism Myxedema coma (in rare cases), when the bodys level of thyroid hormone becomes extremely low What Is Myxedema, or Advanced Hypothyroidism

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Juvenile and adult worms were carefully washed in phenol red free RPMI medium and subsequently incubated in phenol red free RPMI medium supplemented with 5.5 mM D-glucose, penicillin-streptomycin and 5% heat inactivated fetal bovine serum and at 37 C in a 5% CO 2 incubator overnight