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Toxins (Basel) (2017) 9(4):119

Anti-Inflammatory and Antioxidant Mechanisms Chronic inflammation drives much of the damage associated with aging and disease

In patients with mutations in the C9ORF72 gene, the production of harmful dipeptide repeat proteins further disrupts communication between the nucleus and cytoplasm, impairing cell function

Jahan MS, Nozulaidi M, Khairi M, Mat N (2016) Light-harvesting complexes in photosystem II regulate glutathione-induced sensitivity of Arabidopsis guard cells to abscisic acid

However, levels of glutathione decrease due to factors like aging, UV exposure, and poor lifestyle habits

Saylor et al., 2016), rather than T-cells, which largely drive peripheral pathogenesis (Deeks et al., 2015)