Applicable Procedure Codes: 0737T, 27412, 27415, 27416, 27418, 27437, 27438, 27440, 27441, 27442, 27443, 27446, 27447, 27486, 27487, 27568, 27569, 27664, 27665, 29866, 29867, 29868, 29870, 29871, 29873, 29874, 29875, 29876, 29877, 29879, 29880, 29881, 29882, 29883, 29884, 29885, 29886, 29887, 29888, 29889, G0428, J7330, S2112
Mechanism Diagram GHK-Cu vs Growth Peptides (Key Differences) GHK-Cu - Copper binding tripeptide - Acts locally in tissue - Modulates gene expression and ECM remodelling - Not endocrine - Does not elevate GH or IGF-1 GH Secretagogues (e.g., Ipamorelin, Hexarelin, MK-677) - Act via endocrine receptors - Stimulate systemic GH release - Increase IGF-1 - Primarily hormonal These compounds operate in completely different biological domains
Britta Reierson, a family physician specializing in metabolic health and medical director at Knownwell, agrees
Genet 24 , 109132 (2023)
By reactivating sirtuins and supporting mitochondrial function, NAD+ promotes greater cellular energy production and supports natural DNA repair processes
Tzotzos S, Fischer B, Fischer H, Pietschmann H, Lucas R, Dupre G, et al