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Global guidelines from the American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD), and the American Association of Clinical Endocrinology (AACE) now recommend GLP-1 receptor agonists as preferred second-line agents after metformin in type 2 diabetes management, and increasingly as first-line in patients with established or high-risk cardiovascular disease or obesity

However, the agency says it cant rule out a small increase in risk because of the small total number of events in their surveillance systems, and its investigation is ongoing

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Glucagon-like peptide-1 receptor agonists increase solid gastric residue rates on upper endoscopy especially in patients with complicated diabetes: a case-control study

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