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In tolerance assays forty-two hours after the conditioning regimen, shorter preconvulsive latencies than that in healthy mice following an isoniazid treatment (800 mg/kg i.p.) were observed if diazepam (5.0 mg/kg i.p.) was given again to mice previously conditioned with diazepam alone

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and KPV contributes an anti-inflammatory action that could, in principle, create a more favorable healing environment

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Sasaoka T, Ishiki M, Wada T, Hori H, Hirai H, Haruta T, Ishihara H, Kobayashi M (2001) Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis